Classics in Total Synthesis. By K.C. Nicolaou and E. J. Sorensen. Article (PDF Available) in Molecules 3(2) · February with 2, Reads. This book is essential for any synthetic organic chemist.[ ]. K. C. NICOLAOU, E. J. SORENSEN. CLASSICS IN. TOTAL. Page 2. Classics in Total Synthesis K. C. Nicolaou and. – E. J. Sorensen. VCH.

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Classics in Total Synthesis: Similar to its predecessors and completing the trilogy, this textbook analyzes the syntheses in a didactic manner, with several chapters including mini-reviews of key methodologies, and an emphasis on the history, mechanism, scope, and generality of the reactions.

Wiley-VCH – Classics in Total Synthesis III

Nowadays, books that concentrate on niicolaou area of organic synthesis are numerous enough to fill whole inventories of libraries. About the Author K. Classics in Total Synthesis III will surely itself become a classic in the literature on the state of the art of contemporary organic synthetic chemistry. After describing retrosyntheses that have been achieved, and any preliminary synthetic work, the chapter gives a very detailed description of the synthesis of the target structure, including almost all the individual steps.

His impact on chemistry, biology and medicine flows from his research works in nicloaou synthesis and chemical biology described in numerous publications and patens.

All literature references are clearly identified by chapter endnotes, thus allowing rapid access to the primary sources. Graduate students and researchers alike will find this book a gold mine of useful information essential for their daily work.


Book Review: Classics in Total Synthesis – K. C. Nicolaou, E. J. Sorensen

Nicolaou – Winner of the Nemitsas Prize in Chemistry This book is a must for every synthetic chemist. On the other hand, the great success of ib series does support a continuation of totaal style in its present form. For easy reference, key intermediates are also shown in the margins. Important formulas are, in addition, depicted in the margin, next to the passage where they are mentioned in the text.

KGaA – Provider – www. He is the recipient of many prizes, awards and honors. This alone is one of the great strengths of the book, and provides every synthetic chemist with an excellent pool claszics the solution of his or her own synthetic problems. It becomes fastly understandable, why a method in a certain step was selected.

Classics in Total Synthesis III: Further Targets, Strategies, Methods

But of that multitude, only a few books have been as outstanding in recent years as the series Classics in Total Synthesis, written by K. Most synthesis of natural products require a special skill: A wonderful tool for nicollaou and teaching and a must-have for all current and future organic and biochemists. Further Targets, Strategies, Methods. He currently is a post-doctoral fellow in Professor Nicolaou’s laboratory.

The review of asymmetric halogenation reactions Chapter It is a large joy to read “Classics in Total Synthesis”, even if one must ask himself amazedly if he had come on such ingenious synthesis ways.


He explains all the key steps of the synthetic pathway, highlighting the major developments in blue-boxed sections and contrasting these to other synthetic methods.

The very instructive concept of discussing and comparing several different syntheses of a target structure in a parallel classids, which was introduced in the second volume of this series, has now been further developed in a clever way.

Excellent graphics and two colours throughout: The main author Nicolaou is a top-notch US chemist, who is now regarded as the world’s leading synthetic chemist. Added to Your Shopping Cart.

The chapter ends with a short summary and a well-chosen, detailed, and extensive list of references. Added to Your Shopping Cart. Nicolaou compiles here the important strategies and tools employed to construct complex molecules.

Classics in Total Synthesis

That Woodward used “State of the Art” – techniques purposefully and with an ingenious planning skill, is appreciated in this book. The layout fotal this book has only been slightly changed compared with previous volumes.

Every synthetic organic chemist will want to have a copy on his or her desk. After two years as a medicinal chemist at Enanta Pharmaceuticals, he began graduate studies at The Scripps Research Institute under the guidance of Professor K.